Oliveria decumbens, a bioactive essential oil: Chemical composition and biological activities
Authors
Abstract:
Oliveria decumbens is an aromatic plant traditionally used for treatment of infections and gastrointestinal diseases. In the present study, the volatile oil of the plant was obtained by hydrodistillation and analyzed by GC-MS. In addition, antibacterial and anti-Helicobacter pylori activities of this essential oil were determined using disc diffusion and agar dilution methods, respectively. Insecticidal activity was assessed through topical and fumigation application of the essential oil to cabbage looper larvae. Acetylcholinesterase (AChE) inhibition by the essential oil was examined using Ellman’s method. Furthermore, its cytotoxic potential against three different cancer cell lines was assessed using the MTT assay. The phenolic monoterpenoids, thymol (38.79%) and carvacrol (36.3%) were identified as major constituents of the essential oil. We observed significant antibacterial activity of the essential oil against H. pylori (MIC=20.4 µg /mL) as well as other tested bacteria, except for Pseudomonas aeruginosa. O. decumbens essential oil showed significant toxicity to cabbage looper larvae with LD50 value of 52.1 µg /larva following topical and fumigant administration. O. decumbens essential oil was considerably inhibitory to acetylcholinesterase activity (IC50=0.117 µg/ml). Cytotoxic assay of the volatile oil resulted in IC50 =0.065, 0.104 and 0.141 μg/mL for MCF-7, T47D and MDA- MB-231 cell lines, respectively. According to our data, this species with high concentrations of thymol and carvacrol could be considered as a natural source for pharmaceutical products.
similar resources
Chemical Composition and Biological Activities of Essential Oil and Methanol Extract of Teucrium scordium
In this study, the chemical composition of the essential oil of Teucrium scordium was studied using capillary GC and GC/MS instruments. In addition, the antimicrobial and cytotoxic activities of the oil and methanol extract were evaluated by disc diffusion and MTT assays, respectively. Forty-three volatile components were identified from the oil of aerial parts, representing of 98....
full textChemical composition and biological activities of essential oil and methanol extract of Scrophularia umbrosa
Background and objectives: Scrophularia umbrosa Dumort is used as a traditional herb in China. In this study, chemical profile, free radical suppression capability, general toxicity and cardiovascular activities of the volatile compounds from S. umbrosa were investigated. Moreover, methanol (MeOH) extract of rhizomes were analyzed to purify and identify the co...
full textChemical Composition and Antimicrobial Activity of Oliveria decumbens Volatile Oil from West of Iran
Background: Oliveria decumbens Vent. is an endemic plant of Flora Iranica that grows in high temperature areas of south and west of Iran. It is used for indigestion, diarrhea, abdominal pain and fever in traditional medicine. Objective: In this investigation, chemical composition and antimicrobial effects of Oliveria decumbens has been studied. Methods: The essential oil of aerial parts o...
full textChemical Composition and Some Biological Activities of Artemisia marschalliana Essential Oil
Background and objectives: The aerial parts of Artemisia marschalliana Sprengel as an indigenous species of genus Artemisia in the East Azerbaijan province of Iran, was subjected to phytochemical analysis, as well asanti-proliferative, free-radical-scavenging and anti-malarialactivities. Methods: The chemical composition of the essential oil o...
full textChemical Composition and Biological Activities of Lemon (Citrus limon) Leaf Essential Oil
Background and Objectives: Essential oils and their compounds are getting increasing interest due to their multipurpose functionals as alternatives to the artificial preservatives. The aim of this study was to extract and identify the volatile constituents of essential oil of Citrus lemon leaf and to evaluate its antioxidant and antibacterial abilities. Materials and Methods: The essential oil...
full textMy Resources
Journal title
volume 18 issue 1
pages 412- 421
publication date 2019-01-01
By following a journal you will be notified via email when a new issue of this journal is published.
Hosted on Doprax cloud platform doprax.com
copyright © 2015-2023